Botulism

Last Updated: 2023-07-07

Author(s): Anzengruber F., Navarini A.

ICD11: 1A11.Z

  • Tetanus

Notifiable infection with Clostridium botulinum.

  • Transmission
  • Smoked foods, canned foods, honey
  • C. botulinum secretes toxins, inhibiting the presynaptic release of acetycholine

  • Muscle paralysis
  • Mouth dryness
  • Visual disturbances

  • Anamnesis (what was eaten?)
  • Clinic

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  2. Chalk CH, Benstead TJ , Keezer M. Medical treatment for botulism. Cochrane Database Syst Rev 2014;2:CD008123.
  3. Brown N , Desai S. Infantile botulism: a case report and review. J Emerg Med 2013;45:842-5.
  4. Moreira GM, Cunha CE, Salvarani FM, Goncalves LA, Pires PS, Conceicao FR et al. Production of recombinant botulism antigens: a review of expression systems. Anaerobe 2014;28:130-6.
  5. Webb RP , Smith LA. What next for botulism vaccine development? Expert Rev Vaccines 2013;12:481-92.