Condylomata plana

Last Updated: 2023-07-07

Author(s): Anzengruber F., Navarini A.

ICD11: -

Molluscum contagiosum
Squamous cell carcinoma of the skin (spinocellular carcinoma, SCC)
Granuloma anulare
Lichen ruber planus
Seborrhoeic keratosis
Syphilis
Syringom
Pearly penile papules
Lymphangioma
Fordyce spots
Epidermal cysts
Bowenoid papulosis

Partner should be examined by a doctor in any case!
Inform patients about ping-pong phenomenon, which stands for re-infection by the untreated partner. Therefore, both partners should be treated at the same time!

Topical therapy (mostly off label use!)

Cryotherapy

Application: 2x to 15 seconds.
Note: effective, cheap, briefly uncomfortable for patients.

Immune modulators

Imiquimod

3x weekly for 12 weeks
off-label use:
- Application: 5x/week for several weeks, maximum 16 weeks.
Necessary before ablation of the wart surface.
NWW: redness, itching, burning, erosion of the skin. Pat. to be informed about this before beginning therapy!

Podophyllin/Podophyllotoxin:

Apply 2 times daily for 3 consecutive days. Repeat if necessary
off-label use:
- Apply 2x daily for 3 consecutive days, protecting surrounding skin. Repeat if necessary
KI: < 12y., open wounds, women of childbearing age, contraception recommended until 30 days after therapy, pregnancy, lactation

Sinecatechins ointment green tea extract:

Administer 3 times daily for up to 16 weeks

Trichloroacetic acid 85% (magistral formulation):

Application: 1x/week with cotton swab. Therapy belongs in the hands of a doctor. Also permitted during pregnancy, in case of overdose neutralisation with sodium bicarbonate solution

Removal with CO² laser/electrocautery/curette/excision:

CAVE infectiousness! Especially with lasers and electrocautery. Always wear a face mask or goggles and a mouth guard! Smoke extraction is essential

Other therapies described:

Interferon- β gel application should be carried out for a maximum of 4 weeks.

In Switzerland only available via foreign pharmacy.
Germany: 0, 1 million IU/g, 5x tgl.